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However one major challenge will be to understand how the
2021-05-19

However, one major challenge will be to understand how the diverse actions of D2Rs in multipartite, dopamine-sensitive circuits are coordinated to produce specific behaviors across species. It is possible that emerging techniques for imaging neuronal activity in different neuronal population in beha
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DGK is a key enzyme in glucose uptake
2021-05-18

DGKδ is a key enzyme in glucose uptake in skeletal muscle. Chibalin et al. demonstrated that a decrease in DGKδ expression increases the severity of type 2 diabetes [20]. Additionally, DGKδ expression was increased in people who exhibited enhanced insulin sensitivity after exercise training [56]. Fr
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The preferences for source of FAs for DGAT
2021-05-18

The preferences for source of FAs for DGAT1 and DGAT2 are related to their membrane topologies, subcellular locations, interactions with other proteins or organelles (discussed in the former section), and their differential expression, substrate specificities, and enzyme kinetics. According to UniPr
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TNF a major cytokine that is critical in acute
2021-05-18

TNF-α, a major cytokine that is critical in acute and chronic inflammation, is responsible from chemotaxis, acute phase reactions and endothelial activation (Mahalingam and Karupiah, 1999). Our study showed that TNF-α is increased significantly in the pyelonephritic rats and montelukast displayed an
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Moreover a ligand for fusin has recently been found the
2021-05-18

Moreover, a ligand for fusin has recently been found: the lymphocyte chemoattractant stromal-derived factor-1 (SDF-1) binds to CHO Pregnenolone Carbonitrile transfected with fusin and promotes secondary messenger production (Bleul et al., 1996; Oberlin et al., 1996). A new name, CXCR-4, has been pr
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br Limitations of the study br
2021-05-18

Limitations of the study Possible conflicts of interest Dr. Fayemiwo or SAF has received full financial support from Europe Gilead Sciences Ltd. for his M.Sc. degree programme in Medical Mycology and has been paid for talks on behalf of AstraZeneca and GSK. Caroline Moore or CBM has received
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Previous studies have demonstrated the role of the COMT Val
2021-05-18

Previous studies have demonstrated the role of the COMT Val158Met in response to positive and negative emotional stimuli (Bouhuys et al., 1999, Cohn et al., 2009), a fundamental process involved in well-being (Diener et al., 2009a, Diener et al., 1999, Gross and John, 2003). A handful of studies rep
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Host cell invasion by tachyzoites relies on the
2021-05-18

Host cell invasion by tachyzoites relies on the secretion of numerous secretory proteins and plays a crucial role in maintaining infection [6]. ESA released by tachyzoites are highly immunogenic and induce either antibody-dependent or cell-mediated protective immunity [11], [44], [45]. To investigat
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Enolase as a plasminogen receptor and activator
2021-05-18

Enolase, as a plasminogen receptor and activator localized on the surface of several helminths, can interact with the host fibrinolytic system (Yang et al., 2010, Du et al., 2009, de la Torre-Escudero et al., 2010). The enzyme is also one of excretory/secretory (ES) products in some helminths, such
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Several extragenic cot ts suppressors
2021-05-17

Several extragenic cot-1 (ts) suppressors have been identified. Among them, cytoplasmic dynein, dynactin, and nuclear distribution mutants of N. crassa, as well as an additional gene gul-1 (NCU01197), have been shown to have genetic interactions with cot-1 (Bruno et al., 1996, Seiler et al., 2006, T
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br Materials and methods br
2021-05-17

Materials and methods Results and discussion Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases [28], [29] catalyze oxidative reactions of a range of metabolic processes including the hydroxylation of l-proline and l-lysine residues during the post-translational modification of collagen. Mor
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The first part of the study evaluated the accuracy
2021-05-17

The first part of the study evaluated the accuracy of recomLine IgG and IgG Avidity to date CMV infection: In our study, 83.1% of samples tested matched onset dates compared to 71.9% with VIDAS avidity. Moreover, the number of inconclusive results (intermediate avidity for VIDAS, positive IgG withou
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5(S),6(R)-7-trihydroxymethyl Heptanoate br Materials and met
2021-05-17

Materials and methods Results Discussion We have evaluated the breast cancer prevention potential of PR blockade under conditions that included exposure to progestogens that are relevant to women (progesterone and MPA) and are known to differ in their receptor-binding and down-stream effect
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Additionally in the presented study both the NSE values and
2021-05-17

Additionally, in the presented study both the NSE values and MFI levels of the CD45−CD34 + CXCR7+ angiotensin receptor blockers correlated positively with the inflammatory parameter – CRP. CXCR7 expression has been found to be enhanced during pathological processes such as inflammation and neoplasms
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Among the high value compounds derived from
2021-05-17

Among the high value compounds derived from agricultural residues there are enzymes with industrial application. The extraction processes have been focused on the development of new strategies that guarantee high recovery rates with maximum activity (Nadar et al., 2017). The residues of these two fr
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