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In recent years neuroimaging studies have increasingly demon
2020-05-13
In recent years, neuroimaging studies have increasingly demonstrated acute effects of THC on tcs products function, the vast majority of them involving a cognitive challenge (Bossong et al., 2014b). For example, without affecting performance accuracy, THC caused reductions in activity during encodi
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In patients with CTEPH ET
2020-05-13
In patients with CTEPH, ET-1 levels are raised and have been shown to fall after PEA surgery [24]. After an acute pulmonary embolism there is obstruction of the pulmonary ppar agonist by acute thrombus and elevated levels of ET-1 [28], [30]. Elevated levels of ET-1 have also been observed in air em
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br STAR Methods br Acknowledgments We are grateful to Matthi
2020-05-13
STAR★Methods Acknowledgments We are grateful to Matthias Mayer at ZMBH in Heidelberg for access to his CD-spectrometer and his help in data interpretation. Technical support by Wolfgang Weinig is gratefully acknowledged. This project was financially supported by the European Union as part of t
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br Conclusion Our objective is to
2020-05-13
Conclusion Our objective is to promote cell activity on biomaterials, especially for use in regenerative medicine, by grafting THPs containing collagen-binding sites onto inert substrates. We have previously reported a methodology to derivatize EDC/NHS crosslinked films with photoreactive THPs. T
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Our research has demonstrated that the absolute bioavailabil
2020-05-13
Our research has demonstrated that the absolute bioavailability of oxymatrine, having a similar structure with OSC, was only 6.79±2.52%. About 50% of OSC was converted to its active metabolite SC in vivo; hence, the absolute bioavailability of OSC was speculated to be poor as well [24]. Understandin
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Structural homology modelling Intensive Phyre modelling was
2020-05-12
Structural homology modelling. Intensive Phyre2 modelling [44] was performed using the primary amino IL-2, human recombinant sequence of A1S_0222 as input to generate an atomistic 3D-homology model of A1S_0222. The fit to the SAXS data of the homology model as well as the fit to the data of the E.
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br Conflict of interest br Acknowledgements This work was
2020-05-12
Conflict of interest Acknowledgements This work was funded by the National Science Centre, Poland, grant number N N303 571539. We are greatly indebted to Patrick Fox for help with the final manuscript. Introduction Alkylating agents which interact directly with DNA to form covalent bonds
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Abrahamson and coworkers recently demonstrated a distinct ro
2020-05-12
Abrahamson and coworkers (2009) recently demonstrated a distinct role of the podocyte in preservation and production of mature GBM-components such as α3/4/5(IV)-chains. This group further verified that collagen receptors (integrins) are linked to the 5ar inhibitors of podocytes. In accordance to th
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The present study provides the first evidence that the human
2020-05-12
The present study provides the first evidence that the human uroepithelial mg to mol in vitro respond directly, within 48h, to this carcinogen by promoting extensive vacuolation and DAPK expression. By using the TEM, ICC and Western blotting, we found that the arsenite-induced vacuoles were derived
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br Methods br Results IAA abrogated the
2020-05-12
Methods Results IAA-94 abrogated the protective effects of IPC as it increased myocardial infarction (MI) due to IR injury in vitro (Diaz et al., 1999), and also prevented cyclosporine A mediated cardioprotection (Diaz et al., 2013). Moreover, IAA-94-sensitive currents were observed in cardiac
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Dose response analysis Fig can
2020-05-12
Dose response analysis (Fig. 2) can be performed on Tazobactam sodium salt in culture, in tissue, in animals or even in patients. Many different responses can be measured, including mRNA levels, reporter gene activity, gene product (e.g. enzyme) activity or even physiological functions such as inhib
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br Materials and methods br
2020-05-12
Materials and methods Results Conclusion Conflict of interest Acknowledgements This work was supported by the National Key Research and Development Program of China (2018YFD0400302) and General Program of National Natural Science Foundation of China (31471602). Introduction A sign
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br Materials and methods br Results br Discussion
2020-05-12
Materials and methods Results Discussion In this work, we have studied the contribution of different pathways to the slow but stable progression of replication forks through DNA damaged by MMS [15]. The in vivo analysis of DNA replication forks along a specific chromosome of S. cerevisiae h
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DGK negatively regulated the extension of long
2020-05-12
DGKδ negatively regulated the extension of long axon/neurite (Fig. 4, Fig. 5, Fig. 6). The results strongly suggest that deficiency of DGKδ induces OCD-like behavior by enhancing axon/neurite outgrowth. DGKδ positively regulates growth factor signaling (Crotty et al., 2006). Therefore, DGKδ deficien
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Introduction BRs are well known class of steroid phytohormon
2020-05-12
Introduction BRs are well known class of steroid phytohormones involved in the regulation of key processes of plant growth and development [1], [2], [3], [4], [5]. A lot of attention is driven to BRs in the last decade because of their undeniable functions in promoting Aldicarb synthesis reaction
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