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br STAR Methods br Acknowledgments We thank
2019-08-09
STAR★Methods Acknowledgments We thank the City of Hope core facilities, including the Animal Model Core, Bioinformatic Core, NMR Core, Flow Cytometry Core, and Florescence Microscopy Core for excellent technical support, and NIH grants R01GM086171, R01GM102538, and R01CA212119, R01CA216987, an
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Prostaglandins production and some of their
2019-08-08
Prostaglandins production and some of their possible biological functions have been reported in protozoa, helminths, and fungi organisms, for example amphizoic amoebas of the genus Acanthamoeba and Entamoeba (E. histolytica) produce PGA2, PGE2 and PGF2α [5,6]. PGA2 is believed to be an intrinsic osm
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br Crystal structure of c FMS and binding
2019-08-08
Crystal structure of c-FMS and binding pattern of CSF-1 and IL-34 c-FMS is a 972 amino acids polypeptides containing transmembrane glycoprotein [19]. It contains all the necessary domains required for tyrosine kinase activity, i.e. 512 amino bimatoprost to N-terminal extracellular segment, hydrop
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Another breakthrough towards the understanding of the mechan
2019-08-08
Another breakthrough towards the understanding of the mechanisms responsible for stress-induced relapse to drug seeking behaviour is the evidence published by the group of Wise [34] in which they show that the activation of VTA CRF2 and not CRF1 receptors is responsible for stress-mediated relapse t
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99026msds br Role of CRF receptors in the BNST in
2019-08-08
Role of CRF1 receptors in the BNST in stress-induced relapse to cocaine seeking The seminal work of Stewart and co-workers [19] showed that rats that have extinguished their auto-administration of different drugs of abuse relapse to drug-seeking behaviour when exposed to footshock, even after a 4
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These cognitive deficits may suggest that cognitive
2019-08-08
These cognitive deficits may suggest that cognitive therapy and pharmacotherapy for gambling behavior may ultimately wish to consider genotyping as a means of better targeting treatment approaches. If core cognitive deficits are shown consistently in certain subgroups of gamblers based on genotype,
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The authentic PPase was purified from
2019-08-07
The authentic PPase was purified from B. subtilis as described previously [21], whereas the recombinant enzyme was purified to homogeneity from E.
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br Materials and Methods br Acknowledgements Authors would l
2019-08-06
Acknowledgements Authors would like to thank Mr. Pritam Naskar and Mr. Dibya Mukherjee for their help.
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br Methods br Results br Discussion There
2019-08-05
Discussion There are two particularly important facets of the present ERK findings relevant to drug conditioning.
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Introduction The term myeloproliferative disorders was first
2019-08-02
Introduction The term “myeloproliferative disorders” was first proposed by William Dameshek in 1951.
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br Phylogenetic analysis KSTDs have rather diverse amino aci
2019-08-01
Phylogenetic analysis — Δ1-KSTDs have rather diverse amino PJ34 hydrochloride sequences.
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br Materials and Methods br Acknowledgements We thank the st
2019-07-31
Acknowledgements We thank the staff of beamlines ID29 and ID30A-1 of the European Synchrotron Radiation Facility.
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Verapamil a calcium channel blocker used clinically
2019-07-30
Verapamil, a calcium channel blocker used clinically as a coronary vasodilator, was amongst the first compounds identified that could reverse MDR and potentiate the effects of MDR1 substrates such as vincristine.
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Impaired dopaminergic systems associated with MA have been
2019-07-29
Impaired dopaminergic systems associated with MA have been well-documented (Walsh and Wagner, 1992, Kim et al., 1999, Nakajima et al., 2004, Shin et al., 2012, Shin et al., 2017b, Dang et al., 2016, Dang et al., 2017b).
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In conclusion we developed a
2019-07-27
In conclusion, we developed a new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model that can be useful for screening both CysLT2 receptor and CysLT1/2 receptor antagonists.
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